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Homeostatic plasticity maintains balance in the cortical circuit through mechanisms of integrating new changes to the system while keeping the system at a baseline. Neuronal firing rates in the visual cortex remain stable despite disruptions like monocular deprivation (MD). Initially, during MD, activity in the deprive...
Hepatitis E virus is a leading cause of acute viral hepatitis with high lethality to pregnant and immunocompromised people, and no reliable treatments. The genome contains a region predicted to be a cysteine protease (PCP) indispensable for viral replication. The N-terminal domain is unstructured and contains cysteines...
Methods: A quasi-experimental design was used, involving 70 first-year dental students at the University of Iowa and approved by the IRB [202401434]. Students were randomly assigned to either a control group (no visual guide) or an experimental group (with the visual guide). Both groups completed a Class IV composite r...
Sulfur (S) is an essential nutrient that plants require for the synthesis of methionine and cysteine. These S-amino acids are building blocks of enzymes and proteins and are needed to produce other S-containing compounds crucial for plant growth, development, and stress response. In legumes such as peas (Pisum sativum...
Results: There were no significant differences between cognitive aids in CPR technical skills such as chest compression rates (110 ±6 compressions per minute (TCA), 108 ±6 compressions per minute (ECA); P=0.5), basic life support cycle length (121 (50) seconds (TCA), 120 (92) seconds (ECA)), respiration rates (9 (3) re...
Cardiopulmonary resuscitationHigh-fidelity manikinCanine cardiopulmonary arrestAdvanced life support
Results: 74 horses were fatally injured. Risk score and probability of fatal injury were exponentially related. The most-at-risk horses has risk scores =6 and had 0.4% of starts but 4% of the musculoskeletal fatalities. Their probability of suffering a fatal injury was 44.6 times >risk score =1 horses. Age was not asso...
A writer’s fictional voice is an act of characterization. It is built upon their obsessions, what they omit, repress, or revise, and the strategies they use to capture the reader’s attention and trust. The voice seeks to surprise the reader. But how does one construct their own voice? What feels authentic in writing?
languages and literatureVoicePoetryhumanities and the arts
Genetic information obtained about one person simultaneously reveals information about their biological relatives, yet considerable variation exists in how families are considered and involved across clinical genetics. This thesis investigates the role of the family in clinical genetics, with the specific aim of determ...
Tuberculosis (TB) is a curable disease caused primarily by the bacterium <em>Mycobacterium tuberculosis</em> (<em>Mtb</em>), yet it continues to claim a life every 20 seconds globally. While New Zealand has a relatively low overall burden of TB, Māori and Pasifika communities are disproportionately affected compared to...
Stroke is a major cause of long-term disability in Aotearoa (New Zealand) and continues to disproportionately affect Māori (Indigenous People of Aotearoa), who experience stroke at younger ages and face poorer outcomes compared with non-Māori. While stroke rehabilitation services in Aotearoa are guided by well-establis...
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