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Sjögren's syndrome (SS) is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands, manifesting predominantly as dryness of the mouth and eyes. It is most commonly diagnosed in middle age, but it can also occur in women of reproductive age, which makes pregnancy in patient...
Head and neck cancers are the sixth most common cancer group worldwide and their surgical treatment most often involves extensive resections that impair basic functions such as chewing, swallowing and speech. Newly formed defects need to be reconstructed to restore these functions, with free flaps being the gold standa...
Robotski kirurški postupciSlobodni tkivni režnjeviPlastic Surgery ProceduresFree Tissue Flaps
Cilj istraživanja: usporediti dugoročne rezultate osikuloplastike parcijalnom i totalnom protezom te odrediti karakteristike bolesnika koje utječu na ishod rekonstrukcije pojedinom metodom. Materijali i metode: provedeno je retrospektivno kohortno istraživanje na uzorku osikuloplastika učinjenih u periodu od siječnja 2...
Hemolytic uremic syndrome (HUS) belongs to a group of rare diseases characterized by the development of thrombotic microangiopathy as their common underlying pathological feature. It is characterized by the simultaneous occurrence of thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney injury. Due to t...
Open fractures are injuries in which the continuity of the bone is interrupted with the fracture communicating with the external environment, which makes them particularly risky due to contamination and damage to soft tissues. They often occur in high-energy traumas (traffic accidents, falls from a height, industrial i...
Trodimenzionalne stanične kulture razvile su se kao odgovor na ograničenja klasičnih dvodimenzionalnih kultura, koje ne mogu vjerno prikazati građu i ponašanje stanica u živom tkivu. Organoidi se najčešće uzgajaju iz embrionalnih, induciranih pluripotentnih i odraslih matičnih stanica, a tijekom rasta i diferencijacije...
matične stanicestem cellsBiomedicina i zdravstvoTemeljne medicinske znanosti
Breast cancer is the leading malignancy among women in Croatia and worldwide. Surgical treatment remains the cornerstone of therapy for localized disease, despite advances in systemic therapy and other treatment modalities. Contemporary surgical techniques such as skin-sparing mastectomy (SSM) and skin and nipple-spari...
Sleep and the circadian rhythm are regulated by a complex interplay of neuroanatomically and neuroendocrinologically interconnected structures, with light serving as the most important external factor for synchronizing the internal biological clock. Intrinsically photosensitive retinal ganglion cells play a key role in...
Kliničke medicinske znanostiretinaOphthalmologyBiomedicina i zdravstvo
Cerebral vasospasm is one of the most important complications of subarachnoid hemorrhage (SAH) and plays a significant role in the development of delayed cerebral ischemia and poor neurological outcomes in patients. It most commonly develops between the 3rd and 14th day after hemorrhage and occurs as a result of comple...
Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by the destruction of pancreatic β-cells and absolute insulin deficiency, whose treatment requires lifelong insulin replacement therapy. The clinical presentation includes polyuria, polydipsia, and polyphagia, while diabetic ketoacidosis (DKA) often...
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