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Bone tissue engineering aims to restore or replace bone defects through the integration of biomaterial scaffolds with appropriate structural and biological cues. However, the repair of complex or large bone defects remains challenging due to the need to simultaneously achieve sufficient mechanical stability, effective...
bone regenerationantimicrobial functionalitysheep bone modelmedical engineering
Breast cancer remains a major global health burden, and microcalcifications are an important feature frequently seen on mammograms. These microcalcifications occur in two distinct chemical forms, calcium oxalate and hydroxyapatite. However, only hydroxyapatite is potentially associated with malignancy. Conventional mam...
In Aotearoa New Zealand, pounamu (jade) remains the most significant taonga (treasure) for Māori, embodying mana (prestige), tradition and spirituality. During the late 19th century, a substantial number of pounamu artefacts were fossicked from archaeological sites, resulting in the loss of their original context and d...
SARS-CoV-2 also encodes many innate immune antagonist genes and is excellent at subverting the host immune response. Immune dysregulation leads to the development of both acute disease, as well as long term disease manifestations called post-acute sequelae of SARS-CoV-2 (PASC). To develop effective therapeutics for pat...
basic medicinemedical and health sciencesCoronavirusesCOVID-19
The consumption of alternative grains has been on the rise in the last couple of years due to their nutritional value, allergen-friendly properties, and sustainability. However, these crops are unable to match wheat flour functionality. Therefore, this dissertation attempts to understand which buckwheat and proso mille...
Building on this conceptual framing, the thesis investigates heat-flow and thermal performance through laboratory tests, Design Builder simulations, and field experiments. Laboratory studies isolate the effects of aeration, pigmentation, and water depth on thermal behaviour, demonstrating that aeration suppresses strat...
Proteomic analysis revealed that, rather than directly interacting with the NGF/TrkA pathway, t-BG treatment significantly altered the expression of proteins associated with iron binding and regulation. These findings suggest that t-BG’s biological activity may be linked to iron homeostasis rather than classical neurot...
The brain’s ability to process sensory information is rooted in its complex neural architecture. In particular, the primary visual cortex (V1) plays a pivotal role in encoding and interpreting dynamic visual stimuli, such as speed and motion. While extensive research has focused on the encoding of basic receptive field...
This thesis examines how reframing post-conflict justice through a synchronised, survivor-centred, and relational lens can more effectively address the war–peace continuum of sexual and gender-based violence (SGBV). Situated at the intersection of feminist theory, relational sociology, peacebuilding, and cultural trans...
ethic of caresexual and gender-based violencesocial sciencestransformative justice
Non-vascular plants, such as mosses (Bryophyta), are abundant and ecologically important members of the vegetation in boreal and Arctic ecosystems, which span an expansive area (>4 million km[superscript 2]) globally. In northern ecosystems, mosses play critical roles in regulating carbon and hydrological cycles. For e...
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