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The temporomandibular joint (TMJ) is a complex ginglymoarthrodial synovial joint that endures various mechanical forces during daily use, but its fibrocartilage exhibits limited self-repair capacity due to its avascular nature. This study aims to bridge critical gaps in TMJ fibrocartilage biology and regenerative thera...
The Gothic begins on Christmas Eve, 1764, with the publication of Horace Walpole’s The Castle of Otranto. Beginning with Walpole’s novel and winding throughout the long nineteenth century, this dissertation argues that one of the Gothic’s defining features is a thematic concern with justice, in particular a justice tha...
calculative justicehuman flourishingpostsecularlanguages and literature
Neural circuits possess a dynamic flexibility to adapt to changing inputs and integrate these experiences into their functional framework to allow an organism to learn, adapt, and survive. This encoding is tightly regulated by the interplay of different mechanisms that enable plasticity, while maintaining the overall s...
Here, we present our investigations into the origins of diverse UV-induced mutations in the model organism Saccharomyces cerevisiae. We find that UVA and UVB radiation produce highly distinct patterns of mutations reflecting the different types of damage inflicted by each. Specifically, UVA is poorly mutagenic and prim...
basic medicineUV mutagenesismedical and health sciencesatypical photoproduct
Inaccessible illustrates the impact of structural inequality, isolation, and neglect on Taos County, New Mexico, in the aftermath of the COVID-19 pandemic. This work explores the ways in which structural inequalities work against a racialized minority, impacting this community’s ability to react to modern threats. From...
Disaster ResponsesociologyRural povertyTaos County, New Mexico
<strong>Background: </strong>The relationship between Obsessive-Compulsive Disorder (OCD) and Chronic Pain is a presently under-researched area. This study aimed to explore the prevalence and impact of OCD, investigated through both OCD 'caseness' and obsessive-compulsive symptoms (OC-S), among individuals with Chronic...
In my dissertation, I analyze the ways in which hegemonic discourse was challenged by the representations of Moriscos, Africans, women and captives within theatrical plays of the seventeenth-century. The representations employed in these texts contest the definition of the exemplary Spanish subject as set forth by the...
This Doctor of Business Administration thesis explores the competencies necessary for effective virtual leadership in a Chinese school (Jurong Country Garden School), where managerial and pedagogical activities transitioned to online platforms during the COVID-19 pandemic (2020-2022) and have continued to influence pos...
By equipping T cells with chimeric antigen receptors (CARs), their targeting can be rerouted to selectively destroy blood-based cancer cells. The recent development of CAR T cell therapies has revolutionised the treatment of relapsed/refractory cancers and provides new hope to patients that would otherwise face termina...
medical and health sciencesclinical medicineCAR T cellCell Therapy
This study examines the vlogging practices of Chinese expatriates in Africa (2015–2024) to understand how digital technology’s empowering potential is mediated by platform logics, transforming into complex, often unforeseen realities. It identifies new scripts of distant African others crafted for Chinese audiences, un...
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