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Long-term memory consolidation is a dynamic biological process that relies on activity-dependent transcription, epigenetic regulation, and proteostasis to drive cellular and circuit-level adaptations to experience-induced neuronal activity. Although these processes constitute three mechanistic facets of long-term memor...
Chapter 3 utilizes data from a cluster randomized controlled trial conducted in the Zinder region of Niger to investigate the role of social networks in amplifying the impact of public health interventions on child nutrition and growth outcomes. The trial included over 2,000 households across 105 villages, implementing...
health sciencesmedical and health sciencesNetwork spilloverDifference-in-Difference
Houge-Janssens Syndrome 1 (HJS1) is a rare neurodevelopmental disorder resulting from heterozygous de novo missense mutations in the PPP2R5D gene, which encodes the δ isoform of the B' regulatory subunit family (B'δ) of protein phosphatase 2A (PP2A), a key serine/threonine phosphatase involved in many cellular function...
Pharmacologyhealth sciencesmedical and health sciencesMitochondrial morphology
In this multi-phase mixed-methods study, I investigated the implementation, adoption, and impact of medical drone technology (MDT) operated by Zipline International Inc. within Ghana’s healthcare system. I began with a one-month ethnographic study, where I conducted 5–10 hours of weekly participant observation and carr...
medical and health sciencesHealth accessHealthcareMedical Drone Technology
This research investigated the possibility of adding borate preservative treatment to the production of cross-laminated timber (CLT) using Douglas-fir and grand fir laminates. The goal was to improve biological durability without harming adhesive bond strength or structural integrity. Experimental approaches based on p...
Borate treatmentMold and decay protectionAdhesive bond performanceCross laminated timber
Insulin resistance and resultant hyperglycemia during type 2 diabetes (T2D) contribute to vascular disease, driving T2D morbidity and mortality. In T2D patients, fasting blood glucose levels directly correlate with rates of hepatic gluconeogenesis (GNG), the de novo synthesis of glucose. GNG requires carbon substrate a...
health sciencesmedical and health sciencesLiverDiabetes
Approximately one billion people live in informal settlements. From the early 2000s, governments and international organisations have adopted community participation as ‘best practice’ in slum upgrading programmes. Two decades later, however, informal settlements continue to experience precarious living conditions and...
Uncertainty over the seasonal hydroclimatic conditions creates significant risks about important aspects of agricultural production (e.g., crop phenology and productivity, irrigation demand, etc.). A portion of the uncertainty in agricultural production is associated with fluctuations in the hydrologic cycle produced b...
El Niño–Southern OscillationWater Use EfficiencySeasonal ForecastDrought
The decades between Poland’s two great uprisings (in 1830-1831 and 1863) were marked by imperial repression of Polish cultural and political life. Polish intellectual circles nevertheless flourished at home and abroad, albeit covertly. Narcyza Żmichowska led a group of educated women known as the “Enthusiasts” (Entuzja...
Taiwan occupies a pivotal geographic position at the intersection of East and Southeast Asia and the Pacific, making it central to discussions of both Neolithic dispersal in Asia and the expansion of Austronesian-speaking populations into Island Southeast Asia and Oceania. Understanding the development of plant subsist...
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