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The institution of motherhood, as theorised by Adrienne Rich in <em>Of Woman Born</em> (1976), is a male defined and controlled institution that has remained a powerful oppressive force in women's lives as they navigate becoming mothers for the first time (O'Reilly, 2020). However, in tandem with the institution of mot...
Student motivation is a well-established predictor of academic engagement and achievement. Despite its importance, motivation is difficult to assess accurately, as it is shaped by multiple, overlapping constructs and contextual factors. This complexity continues to pose challenges for researchers and practitioners seek...
validitymotivationsocial scienceslarge language models
vi small-molecule inhibitors can hijack these built-in dynamics and promote different conformational states of Src. We describe a second experimental setup to dissect the kinetics of opening and closing of all Src phosphorylated states. This Fluorescence Resonance Energy Transfer (FRET) experimental setup would have th...
basic medicinemedical and health scienceskinaseNuclear Magnetic Resonance
Epigenetic alterations, particularly DNA methylation changes, play a critical role in cancer development and progression, offering valuable biomarkers for diagnosis, prognosis, and therapeutic strategies. With advances in high-throughput sequencing technologies, the analysis of DNA methylation data has become increasin...
DNA methylation, cell-free DNA (cfDNA)multi-cancer detectionTransformer modelsdeep learning
Tropical cyclones (TCs) are one of the most destructive natural disasters in the world, causing significant economic damage and numerous fatalities. The United States, particularly the areas along the Gulf Coast, Florida, and the eastern seaboard, have been significantly impacted by these storms over the years; this is...
Tropical cycloneUrban agglomerationRainfall modificationSurface roughness and UHI
Viruses have remarkable structural diversity yet they share a common feature: a highly ordered capsid that protects the viral genome and ensures its safe delivery to the host cells. In this PhD, I used cryogenic electron microscopy (Cryo-EM) single particle analysis (SPA) to study the structural states formed by Seneca...
Chapter 2 describes the polymerization of aromatic diamines with sulfur monochloride (S2Cl2) to yield a new class of highly crosslinked, conjugated polymers containing -NSS- functional groups in the backbone. Twenty poly[N,N’-(phenyldiamino)disulfide]s (polyDNDS) polymers were reported by the polymerization of five str...
Animal–microbe symbioses are fundamental to the biology of nearly all multicellular organisms, yet many questions remain regarding how hosts recognize beneficial microbes and establish stable associations. The symbiosis between the Hawaiian bobtail squid, Euprymna scolopes, and the bioluminescent bacterium Vibrio fisch...
Materials used in tissue engineering and regenerative medicine (TERM) need to be biocompatible, sterile, and functional. TERM materials need to interface with patients’ bodies without activating immune responses that can lead to complications or further illness and injury. While there has been extraordinary progress ma...
Drug-resistance pathogens e.g., Pseudomonas aeruginosa are highly resistant to stress conditions, become hospital monsters, and cause severe infections and death. Because known drugs are inherently inactive to treat these infections, solutions are urgently needed. I aimed to investigate the potential applications of ap...
basic medicinemedical and health sciencesbacterial extracellular vesiclesBioengineering
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