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There is a critical nursing shortage worldwide and newly licensed registered nurses (NLRN) are needed to fill this gap. Within the United States, there are approximately 150,000 NLRN graduated per year. Approximately one out of five NLRN (30,000) will leave the nursing field after the first year, and another 1/3 (20,00...
Pre-licensure nursing studentsmedical and health sciencesBurnoutNewly licensed registered nurses
Current neurobiological theories of sleep/wake regulation and neurobehavioral functioning during sleep loss do not account for trait-like, inter-individual and task-dependent differences. Neuroimaging evidence suggests that aspects of cognition may have dissociable neurological mechanisms which may underlie these task-...
Total sleep deprivationCircadian rhythmsocial sciencesNeurobehavioral functioning
The operation of buildings is a major source of greenhouse gas emissions, accounting for 27% of energy-related carbon dioxide emissions globally. There is large potential for reduction in these emissions through energy efficiency improvements and optimised operation of buildings.Models of building energy consumption ar...
other engineering and technologiesSolar gainengineering and technologyHidden Markov models
The overall hypothesis for this thesis is that miRNAs are altered during infection with Leishmania spp. that causes VL (L. donovani and L. infantum) and those miRNAs may have the ability to decrease the expression of pro-inflammatory genes, contributing to the systemic immune suppression seen in VL. This was investigat...
Exosomehealth sciencesmedical and health sciencesLeishmaniasis
Findings challenge the GIM, which predicts that greater gender equality and increased empowerment lead to higher tobacco use among women. Instead, across all studies, higher educational attainment consistently emerged as a protective tobacco use factor. In one study, gender equality narratives did not elevate smoking r...
Cells generate highly dynamic branched F-actin structures which are found in different locations to facilitate specific cellular processes. For example, they are found at sites of endocytosis, phagocytosis, and at the leading edge of migrating cells. These densely arborized actin networks are assembled by the Arp2/3 co...
basic medicinemedical and health sciencesBiochemistry
Colorectal cancer (CRC) remains a global health burden, with rectal cancer comprising approximately one-third of these cases. The standard treatment for locally advanced rectal cancer is neoadjuvant chemoradiotherapy (nCRT) followed by surgery, yet patient responses are highly variable; around 20% achieve a pathologica...
basic medicineNeoadjuvant chemoradiotherapymedical and health sciencesTumour microenvironment
Nitrogen (N) is an essential nutrient for plant growth and required in relatively high quantities. Plants generally take up N in the form of nitrate and ammonium that are assimilated into amino acids in root plastids or in chloroplasts of mature leaves. Most of the 20 proteinogenic amino acids are produced in the chlor...
Glacier and ice-shelf shear margins are localised zones of intense deformation where flowing ice is in contact with confining valley walls, coastal headlands, or slower-moving ice. Within these zones, ice crystal alignment, grain size, temperature, liquid water content, and brittle damage are modified by and contribute...
The evidence obtained during the last two decades has revealed the crucial role of the gut microbiome in human health. Disruptions in the composition and low diversity of the gut microbial community have been associated with various diseases, including inflammatory bowel conditions, diabetes, cancers and neurological d...
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