Buscador de Tesis y publicaciones académicas

Tesis doctoral 2027

Developmental programming of offspring's hepatic molecular phenotype and metabolism following preterm birth

Yakubu, Ibrahim

Preterm birth remains a significant global health concern, affecting one in ten infants and represents a major early life insult with long-term health implications. Preterm birth interrupts normal developmental processes, which leaves the neonate anatomically and metabolically underprepared for extrauterine life. Among...

health sciences medical and health sciences Fatty acid β-oxidation Hepatic metabolism

• University of Otago
• English
• DOI: 10.82348/our-archive.00237

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Tesis doctoral 2027

EPIDEMIOLOGY, DIVERSITY, AND RECURRENCE PATTERNS OF PLASMODIUM OVALE SPECIES IN COASTAL TANZANIA

Carey-Ewend, Kelly

While the prevalence of P. ovale (Po) species appears to be rising in regions where control of P. falciparum (Pf) is improving, their characteristics in endemic regions remain poorly understood. Specifically, the population genomics of P. ovale curtisi (Poc) and wallikeri (Pow) across sub-Saharan Africa, their distribu...

health sciences medical and health sciences

• The University of North Carolina at Chapel Hi...
• English
• DOI: 10.17615/b8nh-sc38

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Tesis doctoral 2027

ROOT HAIR MORPHOGENESIS AND FUNCTION IN THE TEMPERATE GRASS BRACHYPODIUM DISTACHYON

Rosas, Miguel Angel

The root epidermis is essential for interactions with the rhizosphere and facilitates water and nutrient assimilation. Root hairs increase the surface area of the root and show dynamic growth responses to environmental cues. The molecular signals that govern root hair initiation and growth have been well documented in...

biological sciences Brachypodium distachyon function Morphogenesis

• English
• DOI: 10.7273/000007225

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Tesis doctoral 2027

Metabolic interactions between heme, thiol, and mitochondrial pathways in articular chondrocytes

Liman, Suryamin

Joint injury precipitates posttraumatic osteoarthritis (PTOA), primarily driven by oxidative stress and mitochondrial dysfunction in chondrocytes. This dissertation evaluates carbon monoxide (CO) as a potential therapy stimulating antioxidants and mitochondrial metabolism. I hypothesize that CO can mitigate oxidation a...

basic medicine mitochondria medical and health sciences chondrocyte

• English
• DOI: 10.25820/etd.007642

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Tesis doctoral 2027

Analytical techniques for detecting adulteration in mānuka honey

Kodikara, Kaushila Nirmanie

Mānuka honey is an internationally renowned and expensive honey variety produced in New Zealand from the nectar of the <em>Leptospermum scoparium</em> plant. Its distinctive non-peroxide activity (NPA) and a wide array of reputed health benefits have made Mānuka honey a highly sought-after product in both medicinal and...

UHPLC-Q-Orbitrap MS Cheap honey addition Manuka Adulteration Stable Isotope analysis

• University of Otago
• English
• DOI: 10.82348/our-archive.00103

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Tesis doctoral 2027

Engineering Multi-Protein Assemblies with Machine Learning and Experimental Optimization

Dev, Ishaan Joshan

Mammalian Acoustic Reporter Gene (mARG) expression systems are used to express gas vesicle (GV) acoustic contrast agents, enabling visualization of mammalian cell dynamics in living organisms using ultrasound. Further advancement of mARGs is encumbered by all-too-common problems in synthetic biology for mammalian syste...

foundation models mrna structural proteins sequencing

• California Institute of Technology
• English
• DOI: 10.7907/gnma-ay69

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Tesis doctoral 2027

"Spaces of Femininity" in Virginia Woolf’s novels of the 1920s

Yu, Xiaoxi

Despite the substantial emphasis upon space, the visual, and feminism within Woolf Studies, scholars have not explored Woolf's novels of the 1920s through the prism of feminist art historian Griselda Pollock's "spaces of femininity" in a sustained manner. This thesis argues that Pollock's theory, with its emphasis upon...

Griselda Pollock "Spaces of Femininity" Feminist Art Criticism Gender and Space

• University of Otago
• English
• DOI: 10.82348/our-archive.00011

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Tesis doctoral 2027

Mathematical modeling of neuronal dynamics

Liu, Ying

In the first part, we analyze a mean-field model incorporating nonlinear feedback to explore the emergence of spatiotemporal patterns, including standing waves, traveling waves, and modulated waves. By use of Takens-Bogdanov bifurcation, we establish sufficient conditions for the existence and stability of modulated wa...

mathematics natural sciences

• English
• DOI: 10.25820/etd.008059

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Tesis doctoral 2027

The role of mitochondrial calcium transport in neurological diseases

Nguyen, Tam Thi Hong

Mitochondrial Ca2+ uptake and release are crucial for various neuronal processes, including ATP synthesis, synaptic transmission, neurite outgrowth, and gene regulation. However, excessive mitochondrial Ca2+ accumulation can lead to neuronal toxicity via several mechanisms including the opening of the mitochondrial per...

Stroke Tauopathy MCU Epilepsy

• English
• DOI: 10.25820/etd.007958

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Tesis doctoral 2027

Materials Driven Advancements in Superconducting Nanowire Single Photon Detectors

Patel, Sahil R.

Superconducting Nanowire Single-Photon Detectors (SNSPDs) are the premier single-photon counting technology in the near-infrared regime. Operating via a photon-induced phase transition from the superconducting to the normal state, SNSPDs act as highly sensitive digital detectors that now play a critical role in quantum...

Superconducting Engineering Nanowires Materials Science SNSPD

• California Institute of Technology
• English
• DOI: 10.7907/bd0d-2x67

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