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High flow oxygen (HFO) is a relatively new regimen to provide respiratory support in critically ill patients. In the years preceding the COVID-19 pandemic, HFO was introduced into adult critical care because it filled a gap between conventional oxygen therapy (COT) and positive-pressure ventilation. Its adoption, howev...
Monogenic neurodevelopmental disorders (mNDDs) are genetic conditions characterized by a broad spectrum of somatic, developmental, and psychiatric features. Recent advances in stem cell technology have introduced new opportunities to study these mNDDs. Human somatic cells, such as fibroblasts obtained from skin biopsie...
This PhD thesis establishes a comprehensive framework for advancing non-invasive cancer diagnostics through the characterization and combinatorial analysis of small non-coding RNAs (sncRNAs), specifically microRNA isoforms (isomiRs) and tRNA-derived fragments (tRFs). Liquid biopsy offers a minimally invasive alternativ...
As markets and societies become increasingly reliant on digital platform services and infrastructures, businesses and individuals depend ever more heavily on these platforms for access to opportunities. This concentration of control grants platform operators significant power to regulate access. This dissertation, situ...
Diensten van algemeen economisch belangRefusal to dealPublic ServicesLeveringsweigering
Our pupils do more than regulate how much light enters the eyes. Pupil size also changes with cognitive effort, arousal, and attention, which makes it a promising physiological indicator of how people see and think. However, pupil signals are difficult to interpret in everyday situations. While someone is driving, watc...
coverte aandachtpupillary light responsespatial biases of attentioncognitive effort
This dissertation examines the responsible use and potential misuse of big data in paediatric anaesthesiology. Using large multicentre observational databases, it explores how routinely collected clinical data can be used to predict outcomes, generate reference ranges, and answer clinically relevant research questions,...
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide and is closely linked to obesity, type 2 diabetes, and cardiovascular disease. This thesis investigates the prevalence, risk factors, diagnosis, and clinical consequences of MASLD across several high-risk...
medical and health sciencesclinical medicineSDG 3 - Good Health and Well-being
The theme of this PhD thesis is how the uses and consequences of the inundation weapon influenced the landscape formation of North Flanders for 650 years. To this end, all military inundations during that period have been investigated in this area. Human actions include the cutting of dikes, reclamation works, and the...
Earthquakes at subduction zones are among the most powerful natural events on Earth. During the interseismic, coseismic, and postseismic phases, interseismic coupling, co- and postseismic slip along the megathrust, and viscoelastic relaxation in the mantle produce the observed surface displacements. Different combinati...
The debate on homosexuality is polarised. The aim of this research is to discover why Protestants hold different views on homosexuality, whilst they all appeal to Scripture. Thus, homosexuality is a case study that brings to light the differing hermeneutical views of contemporary Protestant theologians. The research qu...
Bert LoonstrahermeneutiekWilliam J. Webb.homosexuality
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