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This dissertation examines what happens after firms achieve high growth. High-growth firms are often portrayed as engines of innovation and job creation, yet most research emphasizes how firms reach rapid expansion and implicitly treats high growth as enduring success. In this dissertation, I shift attention to the pos...
ERIM PhD Series Research in Managementeconomics and businesssocial sciencesSDG 8 - Decent Work and Economic Growth
Non-invasive imaging by means of CCTA, SPECT, PET and CMR is central in diagnosing coronary artery disease (CAD). When obstructive CAD is suspected, patients may undergo invasive coronary angiography (ICA) with fractional flow reserve (FFR), the reference standard for significant epicardial CAD and the main benchmark i...
The spinal cord, despite its central role in sensory and motor integration, remains under investigated compared to the brain. This thesis first addresses key obstacles to non‑invasive electrophysiological recordings from the human spinal cord by developing optimal strategies for removing large cardiac artefacts in elec...
central nervous system, EEG, ESG, signal processingddc:530info:eu-repo/classification/ddc/530
Young fathers are often portrayed as structurally vulnerable, and sometimes, individually resilient. Such perspectives provide a limited understanding of the complex and dynamic experiences of young fatherhood. This dissertation examines how vulnerability and resilience shape young fathers’ experiences and how these dy...
The use of horses in our society comes with a responsibility regarding their health and welfare. Amongst performance-impeding issues, lameness and respiratory pathology are particularly concerning health and welfare. Their early detection relies on regular monitoring of locomotion and physiological statuses. The combin...
This thesis aims to develop and apply novel tissue-engineered in vitro models of theatherosclerotic plaque cap with microcalcifications. These models will be used to study theimpact of microcalcifications within the plaque cap on the collagenous matrix and tissuemechanics, thereby providing insights into the effect mic...
This thesis seeks to understand the role of aging in the biology of the vessel wall and to identify interventions capable of slowing or even reversing that pathophysiology. Its aim is two-fold: (i) to untangle the molecular and hemodynamic pathways that convert chronological time into biological vascular decline, and (...
Heritage plays an important role in the lives of individuals and societies. When heritage belongs to communities or society at large, it acquires a public dimension, making its selection and management the subject of societal and political deliberation. These deliberations take place within heritage policy practices, w...
Although the Standard Model is highly successful, it is not complete. One approach to searching for effects beyond our current understanding of physics is to measure finite-size effects in simple atomic systems through high-precision spectroscopy. In this thesis, we present new measurements of the 2 3S1 -> 2 1S0 transi...
This thesis explores the structural diversity, biological functions, and synthetic accessibility of O-acetylated sialic acids and related complex glycans. It focuses especially on the development of practical chemical and chemoenzymatic methods for producing structurally defined O-acetylated sialoglycans and N-glycan d...
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