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Attention-deficit/hyperactivity disorder (ADHD) is a predominantly childhood-onset neurodevelopmental disorder. However, ADHD is not limited to childhood. The disorder has a highly heterogeneous developmental trajectory from childhood into adulthood, ranging from full remission to persistence of ADHD with adverse outco...
predictingrisicofactorenlongitudinalbroertjes en zusjes
Pregnancy and childbirth are major life events accompanied by profound physical, psychological, and social changes. Although maternal mortality has declined worldwide, many women continue to experience morbidity and functional limitations after childbirth. Traditionally, postpartum recovery has been assumed to be compl...
In Agile software development (ASD) projects requirements are incrementally and iteratively defined, with customer needs frequently expressed in User Stories (USs). However, minimal documentation has been identified as a key challenge for Requirements Engineering (RE) in ASD. Including too little information makes trac...
Antihelmintinis atsparumas yra viena didžiausių šiuolaikinės avių parazitologijos problemų, mažinanti virškinimo trakto nematodų kontrolės veiksmingumą ir kelianti grėsmę tvariai gyvulininkystei. Nepaisant augančios šios problemos svarbos Europoje, Lietuvoje iki šiol trūko reprezentatyvių duomenų apie atsparumo papliti...
Veterinarija / Veterinary (A002)Virškinimo trakto nematodaiSheepMikroagaro lervų vystymosi testas
Antithrombotic therapy is essential for preventing thromboembolic complications, yet its use requires careful balancing benefits and (bleeding) risk. This thesis investigates the management, monitoring, and clinical outcomes of antithrombotic therapy—primarily vitamin K antagonists (VKAs) and antiplatelet agents—across...
The aim of this thesis is to improve patient care and management of plexiform neurofibromas,by focusing on the clinical characteristics, diagnostic methods and treatment.Part I describes the clinical characteristics and management of plexiform neurofibromas.In Chapter 2, we investigate the natural history of NF1 with a...
This thesis consists of two parts. In the first part, the importance of early diagnosisand a good initial treatment response is studied. We assess whether diagnosing PsAquickly after symptom onset results in better clinical outcomes. In addition, we explorethe effect of an early treatment response on PROs over time in...
Software now mediates virtually every facet of daily life, yet each release continues to introduce ethical dilemmas such as addictive design, discrimination, privacy erosion, and manipulation. This dissertation maps the ways in which end‑users articulate these ethical concerns, develops automated methods for their dete...
The rapid growth of urban areas has major consequences for public health. As more people live in urban areas and communities become more diverse, understanding how social environments shape health is increasingly important. This thesis investigates how aspects of the social environment, including connections between pe...
Translation deregulation is a hallmark of cancer, driving oncogenic signaling, therapy resistance, adaptation to environmental conditions, and the production of aberrant proteins. This thesis identifies tRNAs as key regulators of mistranslation in cancer under metabolic and therapeutic stress and explores the potential...
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