Buscador de Tesis y publicaciones académicas

Electrolytes and acid-base in kidney disease

Wieërs, Michiel

Aim of the thesis: 1) To review the reciprocal role between potassium and the kidney using insights from tubulopathies and hypokalemic nephropathy (Chapter 2).2) To review the role of dietary acid load in health and disease (Chapter 3).3) To analyze the clinical characteristics, symptoms and long-term outcomes in Gitel...

Design and Control of Compliant Robotic Systems for Hand Rehabilitation and Tendon-Driven Continuum Robots

JABARI, MOHAMMAD

This thesis investigates the design and control of compliant robotic systems for human-centred healthcare, with a dual focus on wearable hand rehabilitation devices and tendon-driven continuum robots (TDCRs) for minimally invasive interventions. The aim is to develop robotic systems that remain mechanically feasible un...

Moving forward with DCIS and invasive breast cancer

Chootipongchaivat, Sarocha

Breast cancer is a global health concern with 670,000 deaths from breast cancer and 2.3million new cases among women in 2022. It is the most common cause of cancer deathamong women worldwide. Early diagnosis and treatment play a crucial role in reducingbreast cancer mortality. Breast cancer screening allows breast canc...

Gene finding, adaptive optics and clinical management of inherited retinal dystrophies

Heutinck, Pam

Inherited retinal dystrophies (IRD) are a heterogenous group of monogeneticrare eye disorders, characterized by degeneration of the photoreceptors,retinal pigment epithelium and/or choroid.1 IRD is the primary cause ofblindness in the working population.2 Its prevalence ranges from 1:3000-4000 in retinitis pigmentosa t...

Transcriptional programs governing Hematopoetic lineage commitment

Picco, Giulia

Cell-type specification, cell differentiation, and cell maturation during development requireintricate regulation of lineage-specific gene expression. New technological advances haveexpanded the resolution at which we can interrogate gene networks and lineage relationshipsthat determine developmental decisions. This Ph...

Diagnosing and treating adenomyosis

Trommelen, Lisa Marleen

Adenomyosis is a benign condition of the uterus characterized by the presence of endometrial glands and stroma within the myometrium. It is a chronic disease for which no preventive or curative uterine-preserving therapies currently exist. It typically presents with abnormal uterine bleeding, dysmenorrhea, chronic pelv...

Hydrate before you medicate

Coppes, Tristan

Preventing dehydration in vulnerable older adults As climate change leads to more frequent heatwaves, the risk of dehydration is increasing, particularly among older adults and especially those with reduced kidney function. Dehydration can also occur during illnesses such as fever, diarrhoea or vomiting. In these situa...

The Rise of Predictive Mice: How Pharmacological Humanization Advances Preclinical Drug Development

Lentzas, Aristeidis

Despite major advances in anticancer drug development, the successful translation of promising preclinical findings into effective clinical therapies remains a major challenge in oncology. Many drug candidates demonstrate strong efficacy in experimental models but ultimately fail during clinical development due to limi...

Hemidactylus turcicus (Linnaeus, 1758) (Sauria:Gekkonidae)'un Bozcaada Popülasyonunun Termal Biyolojisi

BEGÜM BORAN

Kanatlı Hayvanlarda Newcastle Hastalığına Karşı DNA Aşı Tasarımı

KÜBRA ERDOĞAN