Buscador de Tesis y publicaciones académicas

Aproximaciones genómicas y estudios funcionales de variantes genéticas asociadas con trastornos esqueléticos con baja y alta masa ósea

Patiño-Salazar, Juan David

[spa] Las displasias esqueléticas (DiE), son un grupo heterogéneo de enfermedades con una incidencia poco frecuente y diversas manifestaciones clínicas, que están asociadas a múltiples genes y que pueden presentar fenotipos de alta o baja masa ósea. El diagnóstico preciso de las DiE es difícil desde el punto de vista c...

Zinc finger E-box binding homeobox transcription factors (ZEBs) as pathogenic mediators and therapeutic targets in inflammation and cancer

Han, Lu

[cat] Els factors de transcripció ZEB tenen un paper clau en la transició epitelial-mesenquimal (EMT), la plasticitat cel·lular i en els processos de diferenciació de les cèl·lules immunitàries. Els macròfags són les cèl·lules immunitàries més plàstiques, mostrant un espectre continu de fenotips i funcions, especialmen...

Evolutionary Genomics using long-read sequencing: A case study in Dysdera spiders

Pisarenco, Vadim

[cat] Sens dubte, les tecnologies de seqüenciació han revolucionat les ciències de la vida en tan sols unes dècades, transformant la laboriosa tasca de seqüenciar un sol gen en la generació rutinària de genomes complets. Aquest ràpid progrés ha anat acompanyat del desenvolupament constant de mètodes i eines bioinformàt...

Aromatic and medicinal raw plant materials and their derivatives: evaluation of potential biological activities by bio-guided fractionation approaches

PAVARINO, MARTA

Aromatic and medicinal plants are a rich source of bioactive compounds, including essential oils (EOs), complex mixtures of volatile metabolites with promising applications in the pharmaceutical, food, and cosmetic sectors. This PhD project aimed to investigate the biological activities of EOs through a bio-guided frac...

Practical Static Analysis for JavaScript Security: Scalability and Soundness

Xu, Wenyuan

JavaScript is one of the most widely used programming languages, powering software that ranges from web pages to server-side, desktop, and mobile applications. Its popularity and large ecosystem make it a prime target for attackers. The attack surface is expanded through both vulnerabilities in benign code and the dist...

Assessment of Rainfall Energetic Characteristics Under Natural and Simulated Conditions for Soil Erosion Research

Carollo, F.G. · Lo Bianco, R. · Caruso, R.

Rainfall is the primary driver of soil erosion by water, and its erosive potential depends on the size and velocity distribution of impacting raindrops. Rainfall energetic characteristics are typically estimated using optical disdrometers, specialized and costly instruments whose deployment is generally limited to dedi...

In vitro Evaluation and In vivo Assessment of Bacteriophage Endolysins and Antimicrobial Peptides against Mannheimia haemolytica and Pasteurella multocida associated with Bovine Respiratory Disease

Moqaddes, Sidra

Bovine respiratory disease (BRD) is a major infectious disease of cattle that causes substantial economic losses worldwide. It results from interactions among host stress, viral infections, and bacterial pathogens including Mannheimia haemolytica and Pasteurella multocida. Control relies heavily on antimicrobials; howe...

Refining the genetic landscape of Alzheimer's disease : insights from a novel neuropathological cohort

Celeste Laureyssen

Alzheimer’s disease (AD) is the leading cause of dementia in aging populations, affecting approximately 10% of individuals over the age of 65 and accounting for roughly 70% of dementia cases. While AD is classically characterized by extracellular amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles (NFTs) c...

تأثير التغير المناخي في خصائص مناخ العراق السياحي

Autoría no especificada

Sistema de controle de exoesqueleto de membros superiores

Luiz Fernando Ferreira da Silva · Renan Nascimento e Almeida

Exoesqueletos robóticos são utilizados na área médica para a reabilitação ou para o auxílio de pacientes que tem a movimentação neuro-muscular comprometida. O uso de exoesqueletos se provou eficiente para melhorar o desempenho de pacientes após a sua utilização, mesmo quando não estão mais equipados ao mesmo, além de p...