Buscador de Tesis y publicaciones académicas

Particules colloïdales multifonctionnalisées pour la vectorisation d'un principe actif : vers une nouvelle formulation pour la dermatologie

Choimet, Maëla

L’acné est la dermatose la plus courante dans le monde. Cette pathologie, à causes multiples, peut impliquer des traitements longs dont l’efficacité reste à améliorer. Au niveau topique, le ciblage de la surface cutanée et en particulier des foyers infectieux (impliquant notamment la bactérie P. acnes) est un axe de re...

Keratocyte Depletion by Genetic Manipulation Re-creates Corneal Ectasia in a Mouse Model

Ana C. Acosta · Mei Sun · Isaac Poonen-Honig · Victoria Emerick · y 4 más

Corneal ectasias are a significant cause of vision morbidity worldwide. In humans, corneal ectasias are characterized by tissue mechanical weakening, stromal thinning, and bulging. Previous histopathology studies showed a high rate of keratocyte apoptosis in corneas with ectasia. A mouse model expressing a keratocyte l...

From traditional to digital: Artificial intelligence, transforming ultrasound in rheumatology

Diego Javier Martínez Lozano · Yimy F. Medina · Adriana Beltrán-Ostos · Carlos A. Guillén-Astete

The timing and ecological consequences of the late Pleistocene megafaunal declines on the Isthmus of Panama: Implications for trophic rewilding

Felix Pym · Felipe Franco-Gaviria · Marco Raczka · Gbotemi A. Adediran · y 2 más

Lessons learned in the implementation of graduation programs: The experience of Colombia, Mexico, and Paraguay

Graciela, Teruel-Belismelis · Jorge H, Maldonado · Marlene, Peters-Castilla · Manuel, Triano-Enríquez

The aim of this study is to identify systematic and generalizable strengths and weaknesses in the processes for implementing four graduation programs carried out in Colombia (2), Mexico, and Paraguay in 2015-17. The specific aims are to identify some of the key factors common to these processes and their contribution t...

From Small Parsimony to Horizontal Gene Transfer: Inferring Horizontal Transfer and Gene Loss for Single-Origin Characters

López Sánchez, Alitzel · Scholz, Guillaume E · Stadler, Peter F · Lafond, Manuel

The simple underlying pattern of presence–absence of a character within a species tree provides useful steps to trace complex evolutionary histories. Character-based models such as perfect transfer networks and its galled variant aim to leverage this information to predict horizontal gene transfers. Under the assumptio...

The Robust Multicrew Scheduling and Routing Problem in road restoration

Alfredo Moreno · Douglas José Alem · Michel Gendreau · Pedro Munari

Restoring transportation networks is crucial in the aftermath of disasters due to severe disruptions that hinder emergency response efforts, including delays in relief distribution, search-and-rescue operations, and medical assistance. This logistical activity becomes even more challenging with uncertain repair times,...

The DESI DR1 peculiar velocity survey: Growth rate measurements from the galaxy power spectrum

F. Qin · C. Blake · C. Howlett · R. J. Turner · y 62 más

The large-scale structure of the Universe and its evolution encapsulate a wealth of cosmological information. A powerful means of unlocking this knowledge lies in measuring the auto-power spectrum and/or the cross-power spectrum of the galaxy density and momentum fields, followed by the estimation of cosmological param...

Orthopedic implant surface modification with nanoengineered [YSZ/HAp-Ag]n multilayer coatings to promote osteoblast adhesion and early differentiation

E Lorena Medina · J.J. Vaca-González · Diego Quexada-Rodríguez · Salah Ramtani · y 2 más

Metallic implants frequently face three critical challenges that compromise long-term clinical performance: (i) limited biofunctionality that delays osteointegration, (ii) corrosion processes that deteriorate the implant surface and release harmful ions, and (iii) bacterial biofilm formation, which increases the risk o...

Caribbean and South American team-based strategy to control hypertension (CATCH): Rationale and study design of a cluster randomized trial

Katherine T. Mills · Trevor Ferguson · Jose P. Lopez-Lopez · Jacqueline Duncan · y 12 más

Hypertension disproportionately affects populations in low- and middle-income countries (LMICs), especially in Latin America and the Caribbean, due to its high prevalence and low control rate.To close the knowledge-practice gap for blood pressure (BP) control, we are assessing the effectiveness and implementation of a...