Buscador de Tesis y publicaciones académicas

Usefulness of the global leadership initiative on malnutrition -GLIM- criteria to identify malnutrition in older adults: systematic review and meta-analyses

Gustavo Díaz · Carla M. Prado · Maria Cristina Gonzalez · Maria Paula Rugeles

Malnutrition is highly prevalent among older subjects, yet no universal method for its identification has been established. This study aimed to evaluate the concurrent and predictive validity of the GLIM criteria in older adults.A systematic review and meta-analysis were conducted in five databases involving older adul...

Neural network control insights and strategies in low-cost educational platforms: A pneumatic levitation case study

Juan M. Tello-Monroy · Gustavo A. Acosta-Amaya · Rafael A. Ceballos-Ramírez · Jovani A. Jiménez-Builes

Refinement in radiotherapy treatment for locally advanced cervical cancer: a historic perspective

María Caicedo-Martínez · Andrés F. Arbeláez-Mariño · Lina Arbeláez · Andrew Farach · y 1 más

Locally advanced cervical cancer remains a major global health challenge, with outcomes and access disparities greatest in low-middle income countries. Since the 1999 National Cancer Institute clinical alert endorsing concurrent chemoradiation as standard of care, advances in external beam radiotherapy and brachytherap...

Trends and clinical predictors in ovarian preservation in patients with low-risk endometrial cancer

Alexa Kanbergs · Nuria Agusti · Gabrielle Perkins · Chi-Fang Wu · y 6 más

For premenopausal patients with early-stage endometrial cancer, iatrogenic menopause raises concerns regarding cardiovascular risk, cognitive decline, and loss of future fertility. Although previous studies have demonstrated the safety of ovarian preservation in selected patients with low-risk endometrial cancer, and n...

Discovery of novel metabolites in Colombian specialty coffee via multiplatform untargeted metabolomics during solid-state fermentation

Dolly Margot, Revelo-Romo · Johannes, Sikorski · Selma, Vieira · Nelson Humberto, Hurtado-Gutiérrez · y 3 más

The metabolite composition of Arabica coffee during solid-state fermentation remains insufficiently characterized. This study examined changes in mucilage and endosperm metabolites on a Colombian smallholder farm using gas and liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (GC-QTOF-MS an...

Proportion, Morbidity, and Mortality of Acute Invasive Fungal Rhinosinusitis in Immunocompromised Populations

Estephania, Candelo · Srivatsa Surya, Vasudevan · Gene C, Osuoha · Isaac, Elijah · y 7 más

Importance Acute invasive fungal rhinosinusitis (AIFRS) is a rapidly progressive and potentially life-threatening infection that predominantly affects immunocompromised patients. Recent advances in diagnostic imaging, antifungal therapy, and surgical techniques may have altered its incidence, morbidity, and mortality....

El concierto de grado como espacio para la investigación artística

Adriana Steffania Pérez González

Esta ponencia expone los resultados de una investigación artística centrada en el montaje de un concierto de grado de canto como proceso performativo y reflexivo. Inspirada en la afirmación de Marín (2013), que entiende el concierto como una de las formas más intensas de vivir la música, la propuesta documenta cada eta...

Global, regional, and national burden of Chagas disease, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Cousin, Ewerton · Nascimento, Bruno · Whisnant, Joanna · Zimsen, Stephanie · y 166 más

Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma cruzi, primarily transmitted by infected bugs, but also through contaminated food, transfusions, congenital transmission, and organ transplantation. Chagas disease has acute and chronic phases; the chronic phase can occur decades after i...

Clinical characteristics, diagnosis, and treatment of Cushing’s syndrome: analysis of a multicenter registry in Antioquia, Colombia

Wilfredo Antonio Rivera-Martínez · María Johana Ramírez Castaño · Stefanía Cruz Calderón · Néstor Andrés Díaz Posada · y 8 más

Background: Cushing’s syndrome (CS) is a rare endocrine disorder caused by long-term exposure to excess cortisol and is linked to significant morbidity. Data from multiple centers in Latin America remains limited. Objectives: To describe the clinical, diagnostic, and treatment characteristics of patients with CS in a r...

Paralog interference contributes to the preservation of genetic redundancy

Angel F. Cisneros · Florian Mattenberger · Isabelle Gagnon-Arsenault · Yacine Seffal · y 5 más

Models of gene duplication often assume that loss-of-function mutations neutrally promote the return to the ancestral singleton state. They thus ignore the potential functional interference between duplicated proteins stemming from their physical interactions. Here, we show that for heteromerizing paralogs, such interf...